Eric Dane, widely recognized for his roles in Euphoria and Grey’s Anatomy, has publicly shared that he has been diagnosed with amyotrophic lateral sclerosis (ALS), a debilitating and progressive neurological condition.
At 52, the actor opened up about his health in an exclusive interview with People magazine, where he expressed both gratitude and resilience in the face of the diagnosis. “I’m grateful to have my loving family by my side as we navigate this next chapter,” Dane said. “This is a tough journey, but I’m not walking it alone.”
Despite the weight of the diagnosis, Dane shared that he is still able to work and plans to return to the set of Euphoria for its upcoming third season.
“I feel fortunate that I am able to continue working and am looking forward to returning to set of Euphoria next week,” he said, while also requesting privacy for himself and his family during this sensitive time.
Dane plays Cal Jacobs on the popular HBO teen drama, a role that has become one of his most prominent in recent years. Production for season three is scheduled to begin on Monday.
Before his role on Euphoria, Dane was best known for portraying Dr. Mark Sloan, or “McSteamy,” on the long-running medical drama Grey’s Anatomy, a character he played from 2006.
He has also had significant roles in other well-known series, including Jason Dean in Charmed and Captain Tom Chandler in The Last Ship. His film credits include Marley & Me, Valentine’s Day, and Burlesque, showcasing a versatile acting career that spans both television and film.
Dane is married to actress and model Rebecca Gayheart, with whom he shares two children. He credited his family with being a core source of support as he adjusts to life with ALS.
The condition, also known as Lou Gehrig’s disease, is a rare but serious disorder that leads to the gradual degeneration of motor neurons in the brain and spinal cord.
According to the NHS, motor neurone disease (MND) encompasses several different conditions, but ALS is by far the most common form, affecting nearly 90% of all MND patients.
ALS typically begins with subtle symptoms such as muscle weakness, twitching, or slurred speech. As the disease progresses, it causes increasing paralysis, impacting the patient’s ability to move, speak, swallow, and eventually breathe.
“ALS is relentless,” said a spokesperson for the Muscular Dystrophy Association. “While there is no cure, early intervention and supportive care can help manage symptoms and improve quality of life for a time.”
The prognosis for ALS varies, but on average, patients live three to five years after diagnosis, although some may live much longer.
Dane’s revelation brings fresh attention to a disease that often goes unseen until it has already taken a major toll.
With courage and candor, he’s chosen to face this new chapter in his life publicly, while continuing to pursue the work and family life that define him. “I’m still me,” he said. “And as long as I can, I’ll keep showing up — for my family, my fans, and myself.”